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AIDS 2014: Romidepsin Activates Latent HIV, But Does Not Decrease Viral Reservoir

The HDAC inhibitor romidepsin was able to awaken latent HIV in resting T-cells, causing it to start producing new virus, but this was not associated with a decrease in the size of the viral reservoir in T-cells, researchers reported at the 20th International AIDS Conference this week in Melbourne. This finding suggests that kicking HIV out of hiding will not be adequate for a functional cure without strengthening immune response against the virus.

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AIDS 2014: Maraviroc Fails To Match Truvada for First-Line HIV Treatment

A NRTI-sparing dual antiretroviral regimen containing maraviroc (Selzentry) plus ritonavir-boosted darunavir (Prezista) was found to be less effective than a standard combination with tenofovir/emtricitabine (the drugs in Truvada), according to findings from the MODERN study presented this week at the 20th International AIDS Conference in Melbourne.

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AIDS 2014: Criminalization Fuels HIV/AIDS Epidemic [VIDEO]

The role of stigma, discrimination, and criminalization of people living with or at risk for HIV was among the key themes of the 20th International AIDS Conference (AIDS 2014) taking place this week in Melbourne, Australia. Groups targeted by stigma and criminal law are thought to account for half of HIV infections worldwide.

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AIDS 2014: Law and Policy Must Be Part of the Solution for AIDS [VIDEO]

Reforming laws that criminalize and discriminate against people with HIV and key affected populations is a necessary part of the response to the epidemic, according to renowned Australian jurist the Hon. Michael Kirby, speaking at the 20th International AIDS Conference (AIDS 2014) taking place this week in Melbourne, Australia.

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AIDS 2014: Researchers Discuss Progress Towards an HIV Cure [VIDEO]

Progress along the multi-pronged path towards a cure for HIV was one of the themes at the 20th International AIDS Conference (AIDS 2014), taking place this week in Melbourne. Researchers provided updates on the "Mississippi Baby," a novel assay for detecting low levels of hidden virus in the body, and using the anti-cancer drug romidepsin to reactivate latent virus.

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TAG Releases 2014 HIV, Hepatitis C, and Tuberculosis Pipeline Report

The Treatment Action Group (TAG) and HIV i-Base this week released the latest edition of their annual Pipeline Report, covering new therapies and related technologies for HIV, hepatitis C, and tuberculosis (TB), in conjunction with the 20th International AIDS Conference taking place this week in Melbourne, Australia.

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In Memorium: AIDS 2014 Delegates Lost in Malaysian Airlines Crash

HIVandHepatitis.com expresses condolences to the families, loved ones, and colleagues of passengers on Malaysian Airlines flight MH17, which crashed on Thursday after being hit by a missile. Early reports indicated that more than 100 passengers were on their way to the 20th International AIDS Conference, which starts this Sunday in Melbourne, Australia.

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