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Acute Hepatitis C

CROI 2014: How Fast Does Fibrosis Progress in Acute Hepatitis C Patients with and without HIV?

Liver disease was found to progress slowly in studies of both HIV negative people with newly acquired hepatitis C virus (HCV) and HIV/HCV coinfected people with acute HCV, according to a pair of studies presented at the recent Conference on Retroviruses and Opportunistic Infections.

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Sex, Genotype, and IL28B Pattern Predict Spontaneous HCV Clearance

Women, people with hepatitis C virus (HCV) genotype 1, and those with a favorable IL28B gene pattern are more likely to spontaneously clear HCV without treatment, while those with unfavorable patterns are more likely to benefit from earlier therapy, according to 2 recent studies.

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European Study Does Not See Rapid Long-Term Liver Fibrosis in HIV/HCV Coinfected People

People who are already HIV positive when they acquire hepatitis C virus (HCV) may not experience unusually rapid liver disease progression over the long term, even though the fibrosis progression rate may appear high during the acute stage of infection, according to a European FibroScan study described in the February 15, 2012, issue of Clinical Infectious Diseases.alt

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Combining HCV Med Boceprevir with Boosted HIV Protease Inhibitors Can Lower Drug Levels

HIV/HCV coinfected people who take the HCV protease inhibitor boceprevir (Victrelis) for hepatitis C treatment along with a ritonavir-boosted HIV protease inhibitor may experience drug-drug interactions that reduce concentrations of both drugs to ineffective levels, Merck warned this week.alt

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HCV Can Be Sexually Transmitted Between HIV+ Men

Hepatitis C virus (HCV) is transmitted by sex between HIV positive gay/bisexual men and sexual transmission is responsible for several local epidemics, including one in New York City, according to study findings published recently in the CDC's Morbidity and Mortality Weekly Report.alt

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